Developing a Valid Patient-Reported Outcome Measure

Pre-validation methods for developing a patient reported outcome instrument

BACKGROUND Measures that reflect patients' assessment of their health are of increasing importance as outcome measures in randomised controlled trials. The methodological approach used in the pre-validation development of new instruments (item generation, item reduction and question formatting) should be robust and transparent. The totality of the content of existing PRO instruments for a speci...

Can the outcome of primary care be measured by a Patient Reported Outcome Measure?

The Genetic Counseling Outcome Scale: a new patient-reported outcome measure for clinical genetics services.

The aim of this study was to develop a patient-reported outcome measure (PROM) for clinical genetics services. Previous research was used to develop a draft 84-item questionnaire, which was completed by 527 members of patient support groups. Responses were subjected to exploratory factor analysis (EFA). Parallel analysis was used to identify the number of factors to extract using oblique rotati...

The development of a patient-reported outcome measure for patients with obstructive sleep apnea: the Patient-Reported Apnea Questionnaire (PRAQ)

Background: Obstructive sleep apnea (OSA) is a chronic condition that can have a wide range of consequences for a patient’s health-related quality of life. Monitoring aspects of quality of life in clinical practice has the potential to improve the patient-centeredness of care for patients with OSA. The aim of this article is to describe the development of the Patient-Reported Apnea Questionnair...

Developing and testing a new outcome measure.

Kathryn E. Roach, PhD, PT; Alison A. Linberg, DPT, ATC; Michele A. Raya, PhD, PT, SCS, ATC Health outcome measures are used to assess treatment effectiveness. Historically, survival was the most important health outcome. Treatments were assessed based on whether the patient lived or died. Now in the 21st century, treatments for many injuries and illnesses are so effective that many, if not most...